Conventional and alternative disinfectants on the development of Cándida Albicans

In vitro effect

Authors

  • Giannina Vásquez Lizama Universidad del Alba
  • Nicolás Ramos Pazos Universidad del Alba
  • Roger Yefi Carrasco Universidad del Alba

DOI:

https://doi.org/10.37467/revtechno.v13.4807

Keywords:

Cándida Albicans, Disinfectant, Essential oils, Sodium Hypochlorite, Clove, Cinnamon

Abstract

Cándida Albicans is a commensal fungus that colonizes various surfaces of the body, including the oral mucosa. It has the ability to transition to pathogen in the face of any change in its environment. Forms biofilms resisting various chemical disinfectants. The aim of this study was to evaluate the in vitro efficacy of conventional disinfectants and alternative disinfectants on the development of Cándida Albicans. Alternative disinfectants of cinnamon oil and clove have significantly greater efficacy than conventional sodium hypochlorite disinfectant (p<0.001), which may suggest their use as disinfectants on surfaces contaminated with Cándida Albicans.

References

Aguilar-González, A., & López-Malo, A. (2013). Extractos y aceite esencial del clavo de olor (Syzygium aromaticum) y su potencial aplicación como agentes antimicrobianos en alimentos. Temas selectos de ingeniería de alimentos, 7(2), 35-41.

Aizaga Zurita, S. J. (2017). Efecto antifúngico del Aceite Esencial de Canela (Cinnamomum zeylanicum) al 25%, 50%, 75% y 100% sobre Cándida Albicans ATCC® 10231™ (Thesis, Central University of Ecuador-UCE, Quito, Ecuador). Digital Repository of Central University of Ecuador. http://www.dspace.uce.edu.ec/handle/25000/11016

Akay, C., Karakis, D., Doğan, A., & Rad, A. Y. (2016). Effect of Chemical Disinfectants on Candida Albicans Biofilm Formation on Poly (Methyl Methacrylate) Resin Surfaces: A Scanning Electron Microscope Study. Journal of Advanced Oral Research, 7(2), 21-26.

Álvarez Pérez, J. A., Lizarazo Rincón, L. P., Lozada Gelves, B. S., & Lozada Barragán, A. J. (2015). Conocimientos sobre protocolos de desinfección de impresiones dentales antes y después de una intervención educativa en estudiantes de clínicas odontológicas USTA (Pregraduated thesis, Faculty of Odontology, Saint Thomas University, Bogotá, Colombia). Institutional Repository of University of Saint Thomas University. http://hdl.handle.net/11634/4809

Alarcón Galleguillos, M., & Fernández Da Silva, R. (2013). Aplicación terapéutica del Aloe vera L. en Odontología. Salus, 17(3), 42-50.

Arbeláeza, M. I. A., Verganib, C. E., Barbuglic, P. A., Pavarinad, A. C., Sanitáe, P. V., & Jorgef, J. H. (2020). Long-term effect of daily chemical disinfection on surface topography and Candida Albicans biofilm formation on denture base and reline acrylic resins. Oral Health and Preventive Dentistry, 18, 999-1010.

Aslanimehr, M., Rezvani, S., Mahmoudi, A., & Moosavi, N. (2017). Comparison of Candida Albicans adherence to conventional acrylic denture base materials and injection molding acrylic materials. Journal of Dentistry, 18(1), 61.

Añibarro-Ortega, M., Pinela, J., Barros, L., Ćirić, A., Silva, S. P., Coelho, E., . . . & Coimbra, M. A. (2019). Compositional features and bioactive properties of Aloe vera leaf (fillet, mucilage and rind) and flower. Antioxidants, 8(10), 444.

Barrueto, C. S., & Padova, L. (2013). Efecto antimicrobiano del aceite esencial y del extracto acuoso de canela (Cinnamomum zeylanicum) sobre Cándida Albicans y Streptococcus mutans. Sciéndo, 16(1).

Błaszczyk, N., Rosiak, A., & Kałużna-Czaplińska, J. (2021). The potential role of cinnamon in human health. Forests, 12(5), 648.

Chacón-Jiménez, L., & Rojas-Jiménez, K. (2020). Resistencia a desinfectantes y su relación con la resistencia a los antibióticos. Acta médica costarricense, 62(1), 7-12.

Chandra, J., Kuhn, D. M., Mukherjee, P. K., Hoyer, L. L., McCormick, T., & Ghannoum, M. A. (2001). Biofilm formation by the fungal pathogen Candida Albicans: development, architecture, and drug resistance. Journal of bacteriology, 183(18), 5385-5394.

Chatzivasileiou, K., Kotsiomiti, E., & Vyzantiadis, T.-A. (2019). Effectiveness of Denture Cleansers on Removal of Adherent Candida Albicans Cells from Denture Base Acrylics of Various Roughness. The International Journal of Prosthodontics, 32(2), 196-197.

Chau, V. B., Saunders, T. R., Pimsler, M., & Elfring, D. R. (1995). In-depth disinfection of acrylic resins. The Journal of Prosthetic Dentistry, 74(3), 309-313.

Condò, C., Anacarso, I., Sabia, C., Iseppi, R., Anfelli, I., Forti, L., . . . Messi, P. (2020). Antimicrobial activity of spices essential oils and its effectiveness on mature biofilms of human pathogens. Natural product research, 34(4), 567-574.

Da Silva, F. C., Kimpara, E. T., Mancini, M. N. G., Balducci, I., Jorge, A. O. C., & Koga‐Ito, C. Y. (2008). Effectiveness of six different disinfectants on removing five microbial species and effects on the topographic characteristics of acrylic resin. Journal of Prosthodontics: Implant, Esthetic and Reconstructive Dentistry, 17(8), 627-633.

Dalwai, S., Rodrigues, S. J., Baliga, S., Shenoy, V. K., Shetty, T. B., Pai, U. Y., & Saldanha, S. (2016). Comparative evaluation of antifungal action of tea tree oil, chlorhexidine gluconate and fluconazole on heat polymerized acrylic denture base resin–an in vitro study. Gerodontology, 33(3), 402-409.

Del Pozo, J. L., & Cantón, E. (2016). Candidiasis asociada a biopelículas. Revista Iberoamericana de Micología, 33(3), 176-183.

Dorri, M., Hashemitabar, S., & Hosseinzadeh, H. (2018). Cinnamon (Cinnamomum zeylanicum) as an antidote or a protective agent against natural or chemical toxicities: a review. Drug and chemical toxicology, 41(3), 338-351.

Duche, N. P. V., Benítez, P. G. M., Duche, D. E. M., & Medina, C. A. E. (2022). Estudio comparativo entre aloe vera y oleozón, en el tratamiento de estomatitis subprotésica. Una revisión sistemática. Polo del Conocimiento, 7(10), 370-390.

Egbe, N. E., Dornelles, T. O., Paget, C. M., Castelli, L. M., & Ashe, M. P. (2017). Farnesol inhibits translation to limit growth and filamentation in C. Albicans and S. cerevisiae. Microbial cell, 4(9), 294.

Egbe, N. E., Paget, C. M., Wang, H., & Ashe, M. P. (2015). Alcohols inhibit translation to regulate morphogenesis in C. Albicans. Fungal Genetics and Biology, 77, 50-60.

Francisconi, R. S., Huacho, P. M. M., Tonon, C. C., Bordini, E. A. F., Correia, M. F., Sardi, J. d. C. O., & Spolidorio, D. M. P. (2020). Antibiofilm efficacy of tea tree oil and of its main component terpinen-4-ol against Candida Albicans. Brazilian oral research, 34.

Gavilla, A. A., Romero, L. M., & Moya, X. R. (2020). Potencial antifúngico de extractos vegetales sobre el crecimiento in vitro de Colletotrichum gloeosporioides Penz. Agricultura Tropical, 5(2), 39-45.

Ghazal, A. R. A., Idris, G., Hajeer, M. Y., Alawer, K., & Cannon, R. D. (2019). Efficacy of removing Candida Albicans from orthodontic acrylic bases: an in vitro study. BMC oral health, 19(1), 1-7.

Gregorí Valdés, B. S. (2005). Estructura y actividad de los antifúngicos. Revista Cubana de Farmacia, 39(2), 1-1.

Guerrero Narváez, D. (2017). Efecto de diferentes colutorios sobre microorganismos presentes en prótesis acrílicas: estudio in vitro (Thesis, FAculty of Odontology. Central University of Ecuador (UCE), Quito, Ecuador). Digital Repository of UCE. www.dspace.uce.edu.ec/handle/25000/13214

Gulati, M., & Nobile, C. J. (2016). Candida Albicans biofilms: development, regulation, and molecular mechanisms. Microbes and infection, 18(5), 310-321.

Gómez, C., Salcedo-Moncada, D., Ayala, G., Watanabe, R., Pineda, M., Alvítez-Temoche, D., & Mayta-Tovalino, F. (2020). Antimicrobial efficacy of calcium and sodium hypochlorite at different concentrations on a biofilm of Enterococcus faecalis and Candida Albicans: An in vitro comparative study. J Contemp Dent Pract, 21(2), 178-182.

Gómez Loayza, C. R. (2018). Evaluación in vitro de la eficacia antimicrobiana del Hipoclorito de Calcio al 2, 5% y el Hipoclorito de Sodio al 2, 5% sobre un Biofilm de Enterococcus faecalis y Cándida Albicans (Thesis to qualify for the professional title of dental surgeon, Faculty of Odontology. National Universidad of San Marcos, Lima, Perú). Institutional Repository of National University of San Marcos. http://cybertesis.unmsm.edu.pe/bitstream/handle/20.500.12672/6313/Gomez_lc.pdf?sequence=2

Hamman, J. H. (2008). Composition and applications of Aloe vera leaf gel. Molecules, 13(8), 1599-1616.

Hayran, Y., Sarikaya, I., Aydin, A., & Tekin, Y. H. (2018). Determination of the effective antiCándidal concentration of denture cleanser tablets on some denture base resins. Journal of Applied Oral Science, 26.

Hidalgo, E., & Dominguez, C. (2001). Mechanisms underlying chlorhexidine-induced cytotoxicity. Toxicology in vitro, 15(4-5), 271-276.

Jugreet, B. S., Suroowan, S., Rengasamy, R. K., & Mahomoodally, M. F. (2020). Chemistry, bioactivities, mode of action and industrial applications of essential oils. Trends in Food Science & Technology, 101, 89-105.

Jácome Andrade, M. A. (2019). Efecto antifúngico del aceite esencial del clavo de olor (Syzygium aromaticum) sobre cepas de Cándida Albicans: Estudio In vitro (Thesis, Faculty of Odontology. Central University of Ecuador (UCE), Quito, Ecuador). Institutional Repository of UCE. www.dspace.uce.edu.ec/handle/25000/18228

Karpiński, T., & Szkaradkiewicz, A. (2015). Chlorhexidine–pharmaco-biological activity and application. Eur Rev Med Pharmacol Sci, 19(7), 1321-1326.

Koseki, Y., Tanaka, R., & Murata, H. (2018). Development of antibacterial denture cleaner for brushing containing tea tree and lemongrass essential oils. Dental Materials Journal, 37(4), 659-666.

Kurt, A., Erkose‐Genc, G., Uzun, M., Sarı, T., & Isik‐Ozkol, G. (2018). The effect of cleaning solutions on a denture base material: elimination of Candida Albicans and alteration of physical properties. Journal of Prosthodontics, 27(6), 577-583.

Lu, L., Hu, W., Tian, Z., Yuan, D., Yi, G., Zhou, Y., . . . Li, M. (2019). Developing natural products as potential anti-biofilm agents. Chinese Medicine, 14(1), 1-17. https://doi.org/10.1186/s13020-019-0232-2

Maan, A. A., Nazir, A., Khan, M. K. I., Ahmad, T., Zia, R., Murid, M., & Abrar, M. (2018). The therapeutic properties and applications of Aloe vera: A review. Journal of Herbal Medicine, 12, 1-10.

Marqués-Calvo, M. S., Codony, F., Agustí, G., & Lahera, C. (2017). Visible light enhances the antimicrobial effect of some essential oils. Photodiagnosis and photodynamic therapy, 17, 180-184.

Martínez, A. (1996). Aceites esenciales. J. Nat. Prod, 59(1), 77-79.

Mathé, L., & Van Dijck, P. (2013). Recent insights into Candida Albicans biofilm resistance mechanisms. Current genetics, 59(4), 251-264.

Mesa Arango, A., Bueno Sánchez, J., & Betancur Galvis, L. (2004). Productos naturales con actividad antimicótica. Revista Española de Quimioterapia, 17(4), 325-331.

Moyes, D. L., Wilson, D., Richardson, J. P., Mogavero, S., Tang, S. X., Wernecke, J., . . . Runglall, M. (2016). Cándidalysin is a fungal peptide toxin critical for mucosal infection. Nature, 532(7597), 64-68.

Mutlu-Ingok, A., Devecioglu, D., Dikmetas, D. N., Karbancioglu-Guler, F., & Capanoglu, E. (2020). Antibacterial, antifungal, antimycotoxigenic, and antioxidant activities of essential oils: An updated review. Molecules, 25(20), 4711.

Nabila, V. K., & Putra, I. B. (2020). The effect of Aloe vera ethanol extract on the growth inhibition of Candida Albicans. Med. Glas, 17, 485-489.

Naglik, J. R., Gaffen, S. L., & Hube, B. (2019). Cándidalysin: discovery and function in Candida Albicans infections. Current opinion in microbiology, 52, 100-109.

Omidbeygi, M., Barzegar, M., Hamidi, Z., & Naghdibadi, H. (2007). Antifungal activity of thyme, summer savory and clove essential oils against Aspergillus flavus in liquid medium and tomato paste. Food control, 18(12), 1518-1523.

Pereira, R., dos Santos Fontenelle, R., de Brito, E., & de Morais, S. (2021a). Biofilm of Candida Albicans: formation, regulation and resistance. Journal of Applied Microbiology, 131(1), 11-22.

Pereira, R., dos Santos Fontenelle, R., de Brito, E., & de Morais, S. (2021b). Biofilm of Candida Albicans: formation, regulation and resistance. Journal of Applied Microbiology, 131(1), 11-22.

Radha, M. H., & Laxmipriya, N. P. (2015). Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. Journal of traditional and complementary medicine, 5(1), 21-26.

Riverón Rodríguez, L., & Toro Campeny, A. (2018). Estomatitis subprotésica asociada a Cándida: revisión de la literatura (Undergraduated Thesis, Faculty of Odontology. University Finis Terrae of Chile). Institutional Repository of University Finis Terrae. http://hdl.handle.net/20.500.12254/789

Rocha, G. d. S. R., Duarte, T. N., de Oliveira Corrêa, G., Nampo, F. K., & de Paula Ramos, S. (2020). Chemical cleaning methods for prostheses colonized by Candida spp.: A systematic review. The Journal of Prosthetic Dentistry, 124(6), 653-658.

Ruiz, E. F., & Infectólogo, P. (2013). Antisépticos y desinfectantes. Asociación Mexicana de Infectología Clínica AC, 33(1).

Ruiz-Gaitán, A., & del Pozo, J. L. (2021). AmBisome, tres retos: infección por Cándida auris, infección del sistema nervioso central e infección asociada a biopelículas. Revista Iberoamericana de Micología, 38(2), 84-90.

Salles, M. M., Badaro, M. M., Arruda, C. N. F. d., Leite, V. M. F., Silva, C. H. L. d., Watanabe, E., . . . Paranhos, H. d. F. O. (2015). Antimicrobial activity of complete denture cleanser solutions based on sodium hypochlorite and Ricinus communis–a randomized clinical study. Journal of Applied Oral Science, 23, 637-642.

Shafiei, M., Peyton, L., Hashemzadeh, M., & Foroumadi, A. (2020). History of the development of antifungal azoles: A review on structures, SAR, and mechanism of action. Bioorganic Chemistry, 104, 104240.

Sharma, A., Rajendran, S., Srivastava, A., Sharma, S., & Kundu, B. (2017). Antifungal activities of selected essential oils against Fusarium oxysporum f. sp. lycopersici 1322, with emphasis on Syzygium aromaticum essential oil. Journal of bioscience and bioengineering, 123(3), 308-313.

Souza, V. V. M. A., Almeida, J. M., Barbosa, L. N., & Silva, N. C. C. (2022). Citral, carvacrol, eugenol and thymol: antimicrobial activity and its application in food. Journal of Essential Oil Research, 1-14.

Tasso, C. O., de Oliveira Zoccolotti, J., Ferrisse, T. M., Malavolta, I. F., & Jorge, J. H. (2020). Effectiveness of Disinfectant Liquid Soaps in the Reduction of Candida spp Present in Complete Dentures: A Crossover Randomized Clinical Trial. The International Journal of Prosthodontics, 33(6), 620-628.

Tiwari, S., & Gupta, M. (2018). In vitro analysis of antifungal activity of aloe vera extract and aloin on Candida albicans. World Journal of Pharmaceutical Research, 7(15), 415-421.

Tsui, C., Kong, E. F., & Jabra-Rizk, M. A. (2016). Pathogenesis of Cándida Albicans biofilm. Pathogens and disease, 74(4). https://doi.org/10.1093/femspd/ftw018

Ucar Barroeta, A., Rojas de Méndez, G., & Ballester Lelis, A. (2007). Acción de agentes químicos en la eliminación de Cándida Albicans sobre Prótesis Dentales. Acta odontológica venezolana, 45(2), 172-177.

Usano-Alemany, J., Paúl, J. P., & Díaz, S. (2014). Aceites esenciales: conceptos básicos y actividad antibacteriana. Reduca (Biología), 7(2).

Vanegas Meneses, A. F., & Fernández Andrade, J. A. (2022). Efecto de las nanopartículas de plata e hipoclorito de sodio al 5.25% en la inhibición del enterococcus faecalis en los canales radiculares mediante revisión narrativa (Thesis, Faculty of Odontology. Antonio Nariño University). Institutional Repository of Antonio Nariño University. http://repositorio.uan.edu.co/handle/123456789/6054

Vasconcelos, G. L. L., Curylofo, P. A., Raile, P. N., Macedo, A. P., Paranhos, H. F. O., & Pagnano, V. O. (2019). Effect of alkaline peroxides on the surface of cobalt chrome alloy: an in vitro study. Journal of Prosthodontics, 28(1), e337-e341.

Vera Herrera, G. D. R. (2013). Efecto Antimicrobiano In Vitro De Tres Concentraciones Del Aceite Esencial De Cinnamomum Zeylanicum (Canela) Sobre Staphylococcus Aureus, Pseudomonas Aeruginosa Y Cándida Albicans (Bachelor’Thesis in Medicine, National University of Trujillo, Perú). Institutional Repository of National University of Trujillo. https://dspace.unitru.edu.pe/handle/UNITRU/644

Vásquez Carranza, L. (2021). Efecto antimicótico in vitro del aceite esencial de Cinnamomum verum sobre Cándida Albicans de muestras clínicas versus fluconazol 25 μg (Thesis to obtain the professional title of surgeon, Faculty of Health Sciences. César Vallejo University, Trujillo, Perú). Institutional Repository of César Vallejo University. https://repositorio.ucv.edu.pe/handle/20.500.12692/87573

Wang, Y., Ding, Y., Wang, S., Chen, H., Zhang, H., Chen, W., . . . Chen, Y. (2017). Extract of Syzygium aromaticum suppress eEF 1A protein expression and fungal growth. Journal of applied microbiology, 123(1), 80-91.

Yassin, M. T., Mostafa, A. A.-F., & Al-Askar, A. A. (2020). In vitro antiCandidal potency of Syzygium aromaticum (clove) extracts against vaginal candidiasis. BMC complementary medicine and therapies, 20(1), 1-9.

Yu, B., Li, C., Gu, L., Zhang, L., Wang, Q., Zhang, Y., . . . Yin, M. (2022). Eugenol protects against Aspergillus fumigatus keratitis by inhibiting inflammatory response and reducing fungal load. European Journal of Pharmacology, 924, 174955.

Zhang, L., & Tizard, I. R. (1996). Activation of a mouse macrophage cell line by acemannan: the major carbohydrate fraction from Aloe vera gel. Immunopharmacology, 35(2), 119-128.

Published

2023-02-27

How to Cite

Vásquez Lizama, G., Ramos Pazos, N., & Yefi Carrasco, R. (2023). Conventional and alternative disinfectants on the development of Cándida Albicans : In vitro effect. TECHNO REVIEW. International Technology, Science and Society Review Revista Internacional De Tecnología, Ciencia Y Sociedad, 13(3), 1–12. https://doi.org/10.37467/revtechno.v13.4807