https://ojs.bdtopten.com/33011.jszmc/index.php/jszmc en-US Journal of Sheikh Zayed Medical College (JSZMC) 2078-8274 https://ojs.bdtopten.com/33011.jszmc/index.php/jszmc/article/view/218 <p><strong>Background: </strong>Breast cancer is among the commonest of causes of the death caused due to cancer in the females throughout the world.</p> <p><strong>Objective: </strong>To determine the frequency of Seroma formation in patients undergoing Modified Radical Mastectomy after neoadjuvant therapy.</p> <p><strong>Methodology: </strong>Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Surgery, Chandka Medical College Hospital, Larkana from November 2019 to January 2022. A total of 217 diagnosed cases of breast carcinoma patients who underwent a modified radical mastectomy after initially receiving neoadjuvant chemotherapy were selected for this study. Pre-designed proforma was used to collect information related to different variables.</p> <p><strong>Results: </strong>The average age of the women was 47.29±8.38 years. The frequency of seroma formation in patients undergoing modified radical mastectomy with neo-adjuvant therapy was found in 41.94% (91/217). The average seroma Volume and number of resected lymph nodes were 56.64±5.64 ml and 7.59±1.08.</p> <p><strong>Conclusion</strong>: Prediction of seroma formation following Modified Radical Mastectomy with neo-adjuvant therapy remains challenging. We identified no potential risk factors other than the pathological status of the tumor which was associated with an increased frequency of seroma formation.</p> Saira Fatima Umm-e-Rabab Sandano Aisha Shaikh Musrat Sandano Copyright (c) 2022 Journal of Sheikh Zayed Medical College (JSZMC) 2022-08-10 2022-08-10 13 3 10.47883/jszmc.v13i3.218 https://ojs.bdtopten.com/33011.jszmc/index.php/jszmc/article/view/227 <p><strong>Background: </strong>In the current era mortality is very high due to ST-segment elevation myocardial infarction (STEMI) worldwide. One of the most dangerous complications is the formation of left ventricular(LV) thrombus, especially after STEMI, and is considered a major high-risk factor for morbidity and mortality. Although nowadays with primary percutaneous coronary intervention its incidence is reduced but still significant.</p> <p><strong>Objective:</strong> To determine the frequency of left ventricular thrombus in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI).</p> <p><strong>Methodology: </strong>This was a cross-sectional study done at the Department of Cardiology, National Institute of Cardiovascular Disease (NICVD), Karachi from October 3, 2021, to April 2, 2022. Patients who fulfilled the inclusion criteria and were able to give informed consent were enrolled. Primary PCI was performed by a consultant cardiologist and post PPCI all the patients were observed, and transthoracic echocardiography (TTE) was performed to assess the left ventricular thrombus. The data was collected on predesigned proforma.</p> <p><strong> Results:</strong> Mean ± SD of age was 59.39±14.79 years. In the distribution of gender, 101 (73.7%) were male while 36 (26.3%) were female. Left ventricular thrombus was noted in 24 (17.5%) patients.</p> <p><strong>Conclusion</strong>: It is to be concluded that ventricular thrombus is prevalent after primary percutaneous coronary intervention for STEMI patients. Further large-scale work is recommended for the validation of current findings.</p> Muhammad Qasim Khan Rahid Ullah Adnan Fazal Abdul Wahab Buzdar Muhammad Asim Shaikh Farman Ali Copyright (c) 2022 Journal of Sheikh Zayed Medical College (JSZMC) 2022-08-17 2022-08-17 13 3